The adult body (70 kg) is composed of approximately 42 litres of water (approx 60 %). Looking at the composition of the various compartments can help in understanding why some fluids are better at staying in some compartments than others.

All values in mmol/l

Plasma 3/42 =7 %

Interstitial 11/42=26 %

Intracellular 28/42=67 %

Sodium

135-145

145

10

Potassium

4.2

4

157

Calcium

2.4

2.4

<1.0

Magnesium

1.1

1

40

Chloride

112

117

3

Bicarbonate

25

27

7

Protein

15

<0.1

45

Other

8.1

8.7

154 (phosphates)

Table 1 The Composition of the Compartments