Nervous Control

There are two main systems that regulate the cardiovascular system:

1. Nervous

2. Humoral

Nervous control

Rapid responses occur via the autonomic nervous system, with changes being sensed by baroreceptors in the carotid sinus.

Question: What activates the carotid sinus baroreceptors?

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Autonomic nervous system

Humoral system

Speed of response

Seconds-minutes

Minutes-hours

Sensor

Baroreceptors (carotid sinus)

Juxtaglomerular apparatus (kidney)

Effector

Sympathetic outflow

Renin-angiotensin (and subsequently aldosterone)

Response

Vasoconstriction + tachycardia

Vasoconstriction + Na+/H2O retention

Table 1 Response to hypotension

There are two main systems that regulate the cardiovascular system:

1. Nervous

2. Humoral

Nervous control

Rapid responses occur via the autonomic nervous system, with changes being sensed by baroreceptors in the carotid sinus.

Question: What activates the carotid sinus baroreceptors?

Answer: Stretch produced by a rise in blood pressure.

Because they respond to stretch, activation of the baroreceptors results in an inhibitory effect on the cardiovascular system, causing a fall in heart rate and vasodilatation.

Vasoconstriction and tachycardia result from a decrease in activity in the baroreceptors when the blood pressure falls.

Autonomic nervous system

Humoral system

Speed of response

Seconds-minutes

Minutes-hours

Sensor

Baroreceptors (carotid sinus)

Juxtaglomerular apparatus (kidney)

Effector

Sympathetic outflow

Renin-angiotensin (and subsequently aldosterone)

Response

Vasoconstriction + tachycardia

Vasoconstriction + Na+/H2O retention

Table 1 Response to hypotension