Questions and Answers

Question: What chemical class does etomidate belong to and what physicochemical properties does it have?

Answer

Structure of R-etomidate

Question: What chemical class does etomidate belong to and what physicochemical properties does it have?

Answer: It is a carboxylated imidazole derivative, both lipid-soluble and water-soluble, i.e. much more water-soluble than propofol. About 70% is bound to plasma proteins.

Question: What is the dose of etomidate for induction of anaesthesia?

Answer

Structure of R-etomidate

Question: What chemical class does etomidate belong to and what physicochemical properties does it have?

Answer: It is a carboxylated imidazole derivative, both lipid-soluble and water-soluble, i.e. much more water-soluble than propofol. About 70% is bound to plasma proteins.

Question: What is the dose of etomidate for induction of anaesthesia?

Answer: 0.25-0.3 mg/kg.

Question: What is in the ampoule of etomidate?

Answer

Structure of R-etomidate

Question: What chemical class does etomidate belong to and what physicochemical properties does it have?

Answer: It is a carboxylated imidazole derivative, both lipid-soluble and water-soluble, i.e. much more water-soluble than propofol. About 70% is bound to plasma proteins.

Question: What is the dose of etomidate for induction of anaesthesia?

Answer: 0.25-0.3 mg/kg.

Question: What is in the ampoule of etomidate?

Answer: An aqueous solution of etomidate, pH 8.1, stabilized in 35% propylene glycol giving a concentration of 2 mg/ml, i.e. 0.2% etomidate.

Structure of R-etomidate