Presentation

A 1 ml glass vial containing 10 mg. Dilution prior to administration is essential. The contents of the vial should be mixed with 19 ml of normal saline in a 20 ml syringe.

0.5 mg bolus doses should be titrated to effect.

It acts mainly via alpha-adrenoceptors causing an increase in BP via an increase in systemic vascular resistance. It has only minimal effects on beta-adrenoceptors.

It predominantly increases the systemic vascular resistance and has no effect on cardiac contractility.

As for phenylephrine; severe hypotension associated with a normal or fast heart rate.